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KMID : 0358920070340010091
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Journal of the Korean Academy of Pedodontics
2007 Volume.34 No. 1 p.91 ~ p.98
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Sedation evaluation using bis index assessment with and without the added submucosal midazolam
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Lee Young-Eun
Park Mi-Kyung
Kim So-Young
Kim Yoon-Hee
Jung Sang-Hyuk
Baek Kwang-Woo
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Abstract
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The aim of this study was to examine the difference of the depth of sedation using the Bispectral index assessment with and without the added submucosal Midazolam to oral Chloral hydrate and Hydroxyzine for pediatric patients.
Twenty seven sedation cases were performed in this study. Selection criteria included good health(ASA I), 2 to 6 years of age, the need for sedation to receive dental treatment including anesthesia, and restorative procedure over at least two teeth. Patients were randomly classified into one group taking oral Chloral hydrate(60 mg/kg) and Hydroxyzine(1 mg/kg) and the other group recieving Chloral hydrate(60 mg/kg),
Hydroxyzine(1 mg/kg) and submucosal Midazolam(0.1 mg/kg). Nitrous Oxide(50%) was used for both group during sedation. Patients were monitored using a pulse oximeter and a Bispectral monitor. A behavior scale was rated as quiet(Q), crying(C), movement(M), or struggling(S) every 2 minutes watching a recorded videotape.
Analysis showed a significant difference in mean Bispectral index and SD during sedation across two groups(P<0.001). The group of patients injected with submucosal Midazolam in addition to oral Chloral hydrate and Hydroxyzine showed a lower mean Bispectral index and a narrower SD. PR and Sp02 for both groups remained within the normal values.
Submucosal Midazolam improved the sedation quality by deepening sedation depth without compromising safety and enabled the sedation pattern to be kept more stable.
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KEYWORD
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midazolam, bispectal index, sedation, submucosal midazolam, bispectral index
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